The remarkable discoveries continuously brought to light in our country by the archaeologist's trowel lead us to forget that the ancient Greek world was much more extensive than the contemporary Greek state, and that traces of this Greek presence stretch from the Iberian peninsula to beyond the Indus and from the cataracts of the Nile to the Crimea.

Three years after he recovered The Ark of the Covenant. Jones recovered an artifact that he found as a kid, the Cross of Francisco De Coronado from treasure hunters. Now, Jones discovers the history of another biblical artifact called "The Holy Grail". He was also informed that his father, Henry Jones is missing. Jones has to find his father who is looking for the Grail. However, Jones will become involved in the search of the Holy Grail along with his father, as well as fighting the Nazis to reach it.