Animal activists invade a laboratory with the intention of releasing chimpanzees that are undergoing experimentation, infected by a virus -a virus that causes rage. The naive activists ignore the pleas of a scientist to keep the cages locked, with disastrous results. Twenty-eight days later, our protagonist, Jim, wakes up from a coma, alone, in an abandoned hospital.

Horror and Revenge drive this thriller set in the sex and human trafficking underbelly of a nightmarish city where spinal fluid has become the drug of choice...with frightening consequences.

Clive Barker's feature directing debut graphically depicts the tale of a man and wife who move into an old house and discover a hideous creature - the man's half-brother, who is also the woman's former lover - hiding upstairs. Having lost his earthly body to a trio of S&M demons, the Cenobites, he is brought back into existence by a drop of blood on the floor. He soon forces his former mistress to bring him his necessary human sacrifices to complete his body... but the Cenobites won't be happy about this.