In Bus Driver, your job is to transport passengers around an attractive and realistic city. You must drive to a timetable on a planned route, whilst obeying traffic rules, and taking care not to upset or injure your passengers. This makes Bus Driver unlike any other driving game - the experience of driving a bus is very different from blazing through a racing circuit.

Players choose a route to drive from one of the six tiers available and can see a preview of the route and other important information whilst choosing the desired route. Then the bus must be driven along the correct route whilst obeying all traffic rules and stopping at all bus stops. When the game begins, one tier of routes, which includes six buses, is available.